Episodic Luteinizing Hormone Secretion in Man Pulse Analysis, Clinical Interpretation, Physiologic Mechanisms


Authors: 1973, Santen, R. J. and Bardin, C. W.
"These observations suggested that the pattern of LH secretion is similar in both normal individuals and in those with a variety of pathologic conditions. By contrast, the pattern of pulsatile secretion appeared to differ in the following conditions. LH pulses of higher amplitude (333-170%) and lower frequency (1.6-0.24 SEM/6 h) characterized the secretory patterns of women during the luteal phase of the menstrual cycle, suggesting that gonadal steroids may modulate LH pulses. LH pulses of low amplitude (26-2.1%) and frequency (1.3-0.36/6 h) were observed in women with anorexia nervosa."