Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients

Authors:Sjöström, L., Rissanen, A., Andersen, T., Boldrin, M., Golay, A., Koppeschaar, H. P. F. and Krempf, M.
"Orlistat taken with an appropriate diet promotes clinically significant weight loss and reduces weight regain in obese patients over a 2-year period. The use of orlistat beyond 2 years needs careful monitoring with respect to efficacy and adverse events."