Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity


Authors:Bonefeld-Jøregensen, E. C., Andersen, H. R., Rasmussen, T. H. and Vinggaard, A. M.
"In summary, this study indicate that the di-ortho, multiple-chloro substituted biphenyls, PCB#138, PCB#153 and PCB#180, can compete with the binding of the natural ligand to two nuclear receptors and thus possess the ability to interfere with sexual hormone regulated processes."