Inflammation: the link between insulin resistance, obesity and diabetes

Authors: Dandona, P., Aljada, H., Bandyopadhyay, A.
Review of what mechanisms might be involved in the pathogenesis of inflammation given that its presence is a predictor of future onset of diabetes. However, mostly authors just riffing on a questionable causative progressive loop of obesity to diabetes and back again that overlooks the almost innumerable adipocyte interactions and their possible influence on alpha tumor necrosis factor and interleukin-6. Furthermore, there are no data to support that the obese have been, or are, overnourished thereby nullifying the suggestion that overnourishment predisposes the body to a proinflammatory state [site owner opinion of course].